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Activation of ADAM17 by IL-15 Limits Human NK Cell Proliferation

Natural killer (NK) cells are innate cytotoxic lymphocytes that can recognize assorted determinants on tumor cells and rapidly kill these cells. Due to their anti-tumor effector functions and potential for allogeneic use, various NK cell platforms are being examined for adoptive cell therapies. Howe...

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Detalles Bibliográficos
Autores principales: Mishra, Hemant K., Dixon, Kate J., Pore, Nabendu, Felices, Martin, Miller, Jeffrey S., Walcheck, Bruce
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8339566/
https://www.ncbi.nlm.nih.gov/pubmed/34367174
http://dx.doi.org/10.3389/fimmu.2021.711621