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An Early Myelosuppression in the Acute Mouse Sepsis Is Partly Outcome-Dependent

Adult hematopoietic stem and progenitor cells (HSPCs) respond to bacterial infections by expansion to myeloid cells. Sepsis impairs this process by suppressing differentiation of stem cells subsequently contributing to an ineffective immune response. Whether the magnitude of HSPCs impairment in seps...

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Detalles Bibliográficos
Autores principales: Skirecki, Tomasz, Drechsler, Susanne, Jeznach, Aldona, Hoser, Grażyna, Jafarmadar, Mohammad, Kawiak, Jerzy, Osuchowski, Marcin F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8339578/
https://www.ncbi.nlm.nih.gov/pubmed/34367170
http://dx.doi.org/10.3389/fimmu.2021.708670