Specific splice junction detection in single cells with SICILIAN

Precise splice junction calls are currently unavailable in scRNA-seq pipelines such as the 10x Chromium platform but are critical for understanding single-cell biology. Here, we introduce SICILIAN, a new method that assigns statistical confidence to splice junctions from a spliced aligner to improve...

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Detalles Bibliográficos
Autores principales: Dehghannasiri, Roozbeh, Olivieri, Julia Eve, Damljanovic, Ana, Salzman, Julia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8339681/
https://www.ncbi.nlm.nih.gov/pubmed/34353340
http://dx.doi.org/10.1186/s13059-021-02434-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8339681/
https://www.ncbi.nlm.nih.gov/pubmed/34353340
http://dx.doi.org/10.1186/s13059-021-02434-8

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