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Specific splice junction detection in single cells with SICILIAN

Precise splice junction calls are currently unavailable in scRNA-seq pipelines such as the 10x Chromium platform but are critical for understanding single-cell biology. Here, we introduce SICILIAN, a new method that assigns statistical confidence to splice junctions from a spliced aligner to improve...

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Detalles Bibliográficos
Autores principales:	Dehghannasiri, Roozbeh, Olivieri, Julia Eve, Damljanovic, Ana, Salzman, Julia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Short Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8339681/ https://www.ncbi.nlm.nih.gov/pubmed/34353340 http://dx.doi.org/10.1186/s13059-021-02434-8

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