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An EZH2‐dependent transcriptional complex promotes aberrant epithelial remodelling after injury

Unveiling the molecular mechanisms of tissue remodelling following injury is imperative to elucidate its regenerative capacity and aberrant repair in disease. Using different omics approaches, we identified enhancer of zester homolog 2 (EZH2) as a key regulator of fibrosis in injured lung epithelium...

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Detalles Bibliográficos
Autores principales: Le, Huy Q, Hill, Matthew A, Kollak, Ines, Keck, Martina, Schroeder, Victoria, Wirth, Johannes, Skronska‐Wasek, Wioletta, Schruf, Eva, Strobel, Benjamin, Stahl, Heiko, Herrmann, Franziska E, Campos, Alexandre R, Li, Jun, Quast, Karsten, Knebel, Dagmar, Viollet, Coralie, Thomas, Matthew J, Lamb, David, Garnett, James P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8339687/
https://www.ncbi.nlm.nih.gov/pubmed/34224201
http://dx.doi.org/10.15252/embr.202152785