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Aneuploid senescent cells activate NF‐κB to promote their immune clearance by NK cells

The immune system plays a major role in the protection against cancer. Identifying and characterizing the pathways mediating this immune surveillance are thus critical for understanding how cancer cells are recognized and eliminated. Aneuploidy is a hallmark of cancer, and we previously found that u...

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Detalles Bibliográficos
Autores principales: Wang, Ruoxi W, Viganò, Sonia, Ben‐David, Uri, Amon, Angelika, Santaguida, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8339690/
https://www.ncbi.nlm.nih.gov/pubmed/34105235
http://dx.doi.org/10.15252/embr.202052032