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Aurora Kinase A proximity map reveals centriolar satellites as regulators of its ciliary function

Aurora kinase A (AURKA) is a conserved kinase that plays crucial roles in numerous cellular processes. Although AURKA overexpression is frequent in human cancers, its pleiotropic functions and multifaceted regulation present challenges in its therapeutic targeting. Key to overcoming these challenges...

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Detalles Bibliográficos
Autores principales: Arslanhan, Melis D, Rauniyar, Navin, Yates, John R, Firat‐Karalar, Elif N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8339716/
https://www.ncbi.nlm.nih.gov/pubmed/34169630
http://dx.doi.org/10.15252/embr.202051902