Oridonin induces autophagy-mediated cell death in pancreatic cancer by activating the c-Jun N-terminal kinase pathway and inhibiting phosphoinositide 3-kinase signaling

BACKGROUND: Oridonin is a diterpenoid isolated from Rabdosia rubescens that has potent anticancer activity. This study set out to investigate the antitumor effects of oridonin in pancreatic carcinoma (PC) and their underlying mechanisms. METHODS: To investigate the antitumor effects of oridonin, we...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhao, Xin, Zhang, Qi, Wang, Yuanyuan, Li, Shipeng, Yu, Xiangyang, Wang, Botao, Wang, Ximo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8339817/
https://www.ncbi.nlm.nih.gov/pubmed/34422996
http://dx.doi.org/10.21037/atm-21-2630

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8339817/
https://www.ncbi.nlm.nih.gov/pubmed/34422996
http://dx.doi.org/10.21037/atm-21-2630

Ejemplares similares