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Oridonin induces autophagy-mediated cell death in pancreatic cancer by activating the c-Jun N-terminal kinase pathway and inhibiting phosphoinositide 3-kinase signaling

BACKGROUND: Oridonin is a diterpenoid isolated from Rabdosia rubescens that has potent anticancer activity. This study set out to investigate the antitumor effects of oridonin in pancreatic carcinoma (PC) and their underlying mechanisms. METHODS: To investigate the antitumor effects of oridonin, we...

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Detalles Bibliográficos
Autores principales:	Zhao, Xin, Zhang, Qi, Wang, Yuanyuan, Li, Shipeng, Yu, Xiangyang, Wang, Botao, Wang, Ximo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	AME Publishing Company 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8339817/ https://www.ncbi.nlm.nih.gov/pubmed/34422996 http://dx.doi.org/10.21037/atm-21-2630

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