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Silencing c-Jun inhibits autophagy and abrogates radioresistance in nasopharyngeal carcinoma by activating the PI3K/AKT/mTOR pathway

BACKGROUND: Radioresistance plays an important role in the failure of radiotherapy (RT) for nasopharyngeal carcinoma (NPC), leading to poor prognosis. The purpose of this study was to explore the relationship between the expression of the c-Jun oncogene and the prognosis of NPC. In addition, we inve...

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Detalles Bibliográficos
Autores principales: Sun, Yongchu, Chen, Kaihua, Lin, Guoxiang, Wan, Fangzhu, Chen, Li, Zhu, Xiaodong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8339856/
https://www.ncbi.nlm.nih.gov/pubmed/34422997
http://dx.doi.org/10.21037/atm-21-2563