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DMSO reduces the cytotoxicity of anticancer ruthenium complex KP1019 in yeast

Low solubility in aqueous solutions is a significant limitation of the otherwise promising anticancer ruthenium complex KP1019. In laboratory studies, this challenge is often overcome by using DMSO to help drive the drug into solution. Since DMSO was previously shown to alter the bioactivity of plat...

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Detalles Bibliográficos
Autores principales: Davis, Jonathan, Cetto, Anne, Campbell, Mary, Scoggins, Seth, Stultz, Laura, Hanson, Pamela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Caltech Library 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8339913/
https://www.ncbi.nlm.nih.gov/pubmed/34377963
http://dx.doi.org/10.17912/micropub.biology.000436