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Evolution of the Synthesis of Remdesivir. Classical Approaches and Most Recent Advances

[Image: see text] The broad-spectrum antiviral Remdesivir, a monophosphate nucleoside analogue prodrug (ProTide), was repurposed. In May 2020, it received emergency approval by the FDA, being the first drug approved to fight the new coronavirus (COVID-19) disease which targets the virus directly. Th...

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Detalles Bibliográficos
Autores principales: Vargas, Didier F., Larghi, Enrique L., Kaufman, Teodoro S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8340098/
https://www.ncbi.nlm.nih.gov/pubmed/34368522
http://dx.doi.org/10.1021/acsomega.1c03082