Cargando…

Transgenic modeling of Ndr2 gene amplification reveals disturbance of hippocampus circuitry and function

Duplications and deletions of short chromosomal fragments are increasingly recognized as the cause for rare neurodevelopmental conditions and disorders. The NDR2 gene encodes a protein kinase important for neuronal development and is part of a microduplication region on chromosome 12 that is associa...

Descripción completa

Detalles Bibliográficos
Autores principales: Madencioglu, Deniz A., Çalışkan, Gürsel, Yuanxiang, Pingan, Rehberg, Kati, Demiray, Yunus E., Kul, Emre, Engler, Alexander, Hayani, Hussam, Bergado-Acosta, Jorge R., Kummer, Anne, Müller, Iris, Song, Inseon, Dityatev, Alexander, Kähne, Thilo, Kreutz, Michael R., Stork, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8340122/
https://www.ncbi.nlm.nih.gov/pubmed/34381982
http://dx.doi.org/10.1016/j.isci.2021.102868