Comparing syngeneic and autochthonous models of breast cancer to identify tumor immune components that correlate with response to immunotherapy in breast cancer

BACKGROUND: The heterogeneity of the breast tumor microenvironment (TME) may contribute to the lack of durable responses to immune checkpoint blockade (ICB); however, mouse models to test this are currently lacking. Proper selection and use of preclinical models are necessary for rigorous, preclinic...

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Detalles Bibliográficos
Autores principales: Lal, Jessica Castrillon, Townsend, Madeline G., Mehta, Anita K., Oliwa, Madisson, Miller, Eric, Sotayo, Alaba, Cheney, Emily, Mittendorf, Elizabeth A., Letai, Anthony, Guerriero, Jennifer L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8340363/
https://www.ncbi.nlm.nih.gov/pubmed/34353349
http://dx.doi.org/10.1186/s13058-021-01448-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8340363/
https://www.ncbi.nlm.nih.gov/pubmed/34353349
http://dx.doi.org/10.1186/s13058-021-01448-1

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