CRISPR/Cas9 nanoeditor of double knockout large fragments of E6 and E7 oncogenes for reversing drugs resistance in cervical cancer

Drug resistance of tumor cells is always a headache problem in clinical treatment. In order to combat chemotherapy-resistance in cervical cancer and improve treatment effect, we design a CRISPR/Cas9 nanoeditor to knock out two key oncogenes E6 and E7 that lead to drug tolerance. Meanwhile, the delet...

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Detalles Bibliográficos
Autores principales: Li, Xianhuang, Guo, Mingming, Hou, Bei, Zheng, Bin, Wang, Zhiyun, Huang, Mengqian, Xu, Yanan, Chang, Jin, Wang, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8340365/
https://www.ncbi.nlm.nih.gov/pubmed/34353334
http://dx.doi.org/10.1186/s12951-021-00970-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8340365/
https://www.ncbi.nlm.nih.gov/pubmed/34353334
http://dx.doi.org/10.1186/s12951-021-00970-w

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