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Pretreatment of cardiac progenitor cells with bradykinin attenuates H(2)O(2)-induced cell apoptosis and improves cardiac function in rats by regulating autophagy

BACKGROUND: Previous studies have demonstrated that human cardiac c-Kit(+) progenitor cells (hCPCs) can effectively improve ischemic heart disease. However, the major challenge in applying hCPCs to clinical therapy is the low survival rate of graft hCPCs in the host heart, which limited the benefit...

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Detalles Bibliográficos
Autores principales: Wu, Chan, Zhou, Xiao-Xia, Li, Jing-Zhou, Qiang, Hai-Feng, Wang, Yan, Li, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8340370/
https://www.ncbi.nlm.nih.gov/pubmed/34353364
http://dx.doi.org/10.1186/s13287-021-02503-6