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Pretreatment of cardiac progenitor cells with bradykinin attenuates H(2)O(2)-induced cell apoptosis and improves cardiac function in rats by regulating autophagy
BACKGROUND: Previous studies have demonstrated that human cardiac c-Kit(+) progenitor cells (hCPCs) can effectively improve ischemic heart disease. However, the major challenge in applying hCPCs to clinical therapy is the low survival rate of graft hCPCs in the host heart, which limited the benefit...
Autores principales: | Wu, Chan, Zhou, Xiao-Xia, Li, Jing-Zhou, Qiang, Hai-Feng, Wang, Yan, Li, Gang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8340370/ https://www.ncbi.nlm.nih.gov/pubmed/34353364 http://dx.doi.org/10.1186/s13287-021-02503-6 |
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