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Expression of Sonic Hedgehog and pathway components in the embryonic mouse head: anatomical relationships between regulators of positive and negative feedback

OBJECTIVE: The Hedgehog pathway is a fundamental signaling pathway in organogenesis. The expression patterns of the ligand Sonic Hedgehog (Shh) and key pathway components have been studied in many tissues but direct spatial comparisons across tissues with different cell compositions and structural o...

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Detalles Bibliográficos
Autores principales: Sigulinsky, Crystal L., Li, Xiaodong, Levine, Edward M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8340441/
https://www.ncbi.nlm.nih.gov/pubmed/34353359
http://dx.doi.org/10.1186/s13104-021-05714-5