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Differential DNA methylation and changing cell-type proportions as fibrotic stage progresses in NAFLD
BACKGROUND: Non-alcoholic fatty liver disease (NAFLD) is characterized by changes in cell composition that occur throughout disease pathogenesis, which includes the development of fibrosis in a subset of patients. DNA methylation (DNAm) is a plausible mechanism underlying these shifts, considering t...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8340447/ https://www.ncbi.nlm.nih.gov/pubmed/34353365 http://dx.doi.org/10.1186/s13148-021-01129-y |