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E3 ubiquitin ligase TRIM29 promotes pancreatic cancer growth and progression via stabilizing Yes-associated protein 1

BACKGROUND: Pancreatic cancer (PC) is one of the most fatal digestive system cancers. tripartite motif-29 (TRIM29) has been reported as oncogene in several human cancers. However, the precise role and underlying signal cascade of TRIM29 in PC progression remain unclear. METHODS: Western blot, qRT-PC...

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Detalles Bibliográficos
Autores principales: Deng, Xueqiang, Fu, Xiaowei, Teng, Hong, Fang, Lu, Liang, Bo, Zeng, Rengui, Chen, Lian, Zou, Yeqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8340474/
https://www.ncbi.nlm.nih.gov/pubmed/34353343
http://dx.doi.org/10.1186/s12967-021-03007-w