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FHL2 anchors mitochondria to actin and adapts mitochondrial dynamics to glucose supply

Mitochondrial movement and distribution are fundamental to their function. Here we report a mechanism that regulates mitochondrial movement by anchoring mitochondria to the F-actin cytoskeleton. This mechanism is activated by an increase in glucose influx and the consequent O-GlcNAcylation of TRAK (...

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Detalles Bibliográficos
Autores principales: Basu, Himanish, Pekkurnaz, Gulcin, Falk, Jill, Wei, Wei, Chin, Morven, Steen, Judith, Schwarz, Thomas L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8340551/
https://www.ncbi.nlm.nih.gov/pubmed/34342639
http://dx.doi.org/10.1083/jcb.201912077