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FHL2 anchors mitochondria to actin and adapts mitochondrial dynamics to glucose supply

Mitochondrial movement and distribution are fundamental to their function. Here we report a mechanism that regulates mitochondrial movement by anchoring mitochondria to the F-actin cytoskeleton. This mechanism is activated by an increase in glucose influx and the consequent O-GlcNAcylation of TRAK (...

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Detalles Bibliográficos
Autores principales:	Basu, Himanish, Pekkurnaz, Gulcin, Falk, Jill, Wei, Wei, Chin, Morven, Steen, Judith, Schwarz, Thomas L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Rockefeller University Press 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8340551/ https://www.ncbi.nlm.nih.gov/pubmed/34342639 http://dx.doi.org/10.1083/jcb.201912077

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