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Brain areas with normatively greater cerebral perfusion in early life may be more susceptible to beta amyloid deposition in late life
BACKGROUND: The amyloid cascade hypothesis characterizes the stereotyped progression of pathological changes in Alzheimer's disease (AD) beginning with beta amyloid deposition, but does not address the reasons for amyloid deposition. Brain areas with relatively higher neuronal activity, metabol...
Autores principales: | Meier, Irene B., Lao, Patrick J., Gietl, Anton, Vorburger, Robert S., Gutierrez, José, Holland, Christopher M., Guttmann, Charles R.G., Meier, Dominik S., Buck, Alfred, Nitsch, Roger M., Hock, Christoph, Unschuld, Paul G., Brickman, Adam M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8340623/ https://www.ncbi.nlm.nih.gov/pubmed/34368788 http://dx.doi.org/10.1016/j.cccb.2020.100001 |
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