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Retinal Protection by Sustained Nanoparticle Delivery of Oncostatin M and Ciliary Neurotrophic Factor Into Rodent Models of Retinal Degeneration

PURPOSE: Retinitis pigmentosa (RP) is caused by mutations in more than 60 genes. Mutation-independent approaches to its treatment by exogeneous administration of neurotrophic factors that will preserve existing retinal anatomy and visual function are a rational strategy. Ciliary neurotrophic factor...

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Detalles Bibliográficos
Autores principales: Yang, Jing-Yan, Lu, Bin, Feng, Qiang, Alfaro, Jorge S., Chen, Po-Hsuen, Loscalzo, Joseph, Wei, Wen-Bin, Zhang, Ying-Yi, Lu, Shi-Jiang, Wang, Shaomei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8340648/
https://www.ncbi.nlm.nih.gov/pubmed/34347033
http://dx.doi.org/10.1167/tvst.10.9.6