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Molecular docking of potential inhibitors with the mTOR protein

The mTOR (mammalian or mechanistic Target of Rapamycin) is linked with oral cancer. Therefore, it is of interest to study the molecular docking-based binding of paclitaxel (a FDA approved drug for oral cancer) and its analogues with mTOR. Hence, we report the binding features of 10-Deacetyltaxol, 7-...

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Detalles Bibliográficos
Autores principales: Fathima, JH Shazia, Selvaraj, Jayaraman, Sivabalan, Venkatacalam, Rekha, Umapathy Vidhya, Ponnulakshmi, Rajagopal, Vishnupriya, Veeraraghavan, Kullappan, Malathi, Sreekandan, Radhika Nalinakumari, Mohan, Surapaneni Krishna, Vijayalakshmi, Periyasamy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Biomedical Informatics 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8340694/
https://www.ncbi.nlm.nih.gov/pubmed/34393439
http://dx.doi.org/10.6026/97320630017212