Molecular docking analysis of α-Topoisomerase II with δ-Carboline derivatives as potential anticancer agents

The enzyme, α-topoisomerase II (α-Topo II), is known to regulate efficiently the topology of DNA. It is highly expressed in rapidly proliferating cells and plays an important role in replication, transcription and chromosome organisation. This has prompted several investigators to pursue α-Topo II i...

Descripción completa

Detalles Bibliográficos
Autores principales: Ayyamperumal, Selvaraj, DJ, Dhananjay, Tallapaneni, Vyshnavi, Mohan, Surender, S, Basappa, Selvaraj, Jubie, Joghee, Nanjan Moola, MJN, Chandrasekar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Biomedical Informatics 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8340707/
https://www.ncbi.nlm.nih.gov/pubmed/34393444
http://dx.doi.org/10.6026/97320630017249

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8340707/
https://www.ncbi.nlm.nih.gov/pubmed/34393444
http://dx.doi.org/10.6026/97320630017249

Ejemplares similares