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Molecular docking analysis of α-Topoisomerase II with δ-Carboline derivatives as potential anticancer agents
The enzyme, α-topoisomerase II (α-Topo II), is known to regulate efficiently the topology of DNA. It is highly expressed in rapidly proliferating cells and plays an important role in replication, transcription and chromosome organisation. This has prompted several investigators to pursue α-Topo II i...
Autores principales: | Ayyamperumal, Selvaraj, DJ, Dhananjay, Tallapaneni, Vyshnavi, Mohan, Surender, S, Basappa, Selvaraj, Jubie, Joghee, Nanjan Moola, MJN, Chandrasekar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Biomedical Informatics
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8340707/ https://www.ncbi.nlm.nih.gov/pubmed/34393444 http://dx.doi.org/10.6026/97320630017249 |
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