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Structure-based virtual screening of essential Mycobacterium tuberculosis enzymes AspS and KatG for potential inhibitors

Mycobacterium tuberculosis (TB) is a leading global cause of disease-related death. Recent works have studied metabolic pathways of the mycobacterium, highlighting essential enzymes to target via competitive inhibition through computational molecular modeling to suppress the organism's life cyc...

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Detalles Bibliográficos
Autores principales: Collins, Andrew P, Abdelfattah, Waleed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Biomedical Informatics 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8340718/
https://www.ncbi.nlm.nih.gov/pubmed/34393424
http://dx.doi.org/10.6026/97320630017101