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The long‐term prognosis of hippocampal neurogenesis and behavioral changes of offspring from rats exposed to valproic acid during pregnancy

AIM: In pregnant women with epilepsy, it is essential to balance maternal safety and the potential teratogenicity of anticonvulsants. Recently, growing evidence has indicated that valproic acid (VPA) can produce postnatal congenital malformations and impair cognitive function. However, the mechanism...

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Detalles Bibliográficos
Autores principales: Ito, Masanobu, Kinjo, Tomoya, Seki, Tatsunori, Horie, Junko, Suzuki, Toshihito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8340817/
https://www.ncbi.nlm.nih.gov/pubmed/33949804
http://dx.doi.org/10.1002/npr2.12181