Fragment-based covalent ligand discovery

Targeted covalent inhibitors have regained widespread attention in drug discovery and have emerged as powerful tools for basic biomedical research. Fueled by considerable improvements in mass spectrometry sensitivity and sample processing, chemoproteomic strategies have revealed thousands of protein...

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Detalles Bibliográficos
Autores principales: Lu, Wenchao, Kostic, Milka, Zhang, Tinghu, Che, Jianwei, Patricelli, Matthew P., Jones, Lyn H., Chouchani, Edward T., Gray, Nathanael S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: RSC 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8341086/
https://www.ncbi.nlm.nih.gov/pubmed/34458789
http://dx.doi.org/10.1039/d0cb00222d

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8341086/
https://www.ncbi.nlm.nih.gov/pubmed/34458789
http://dx.doi.org/10.1039/d0cb00222d

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