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Kava root extracts hinder prostate cancer development and tumorigenesis by involvement of dual inhibition of MAO-A and LSD1

AIM: Here, we aim to evaluate the chemopreventive efficacy of kava root extracts (KRE) in transgenic adenocarcinoma of the mouse prostate (TRAMP) mice and investigate potential molecular targets of kavalactones, the main components of kava. METHODS: TRAMP mice were administrated with KRE formulated...

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Detalles Bibliográficos
Autores principales: Li, Xuesen, Song, Liankun, Xu, Shan, Tippin, Matthew, Meng, Shuan, Xie, Jun, Uchio, Edward, Zi, Xiaolin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8341175/
https://www.ncbi.nlm.nih.gov/pubmed/34368644
http://dx.doi.org/10.20517/jtgg.2021.22