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Evaluating the effect of ionic strength on PNA:DNA duplex formation kinetics

Peptide nucleic acid (PNA) is a unique synthetic nucleic acid analog that has been adopted for use in many biological applications. These applications rely upon the robust Franklin–Watson–Crick base pairing provided by PNA, particularly at lower ionic strengths. However, our understanding of the rel...

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Detalles Bibliográficos
Autores principales: Swenson, Colin S., Lackey, Hershel H., Reece, Eric J., Harris, Joel M., Heemstra, Jennifer M., Peterson, Eric M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: RSC 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8341200/
https://www.ncbi.nlm.nih.gov/pubmed/34458838
http://dx.doi.org/10.1039/d1cb00025j