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Transcriptomic analysis reveals that mTOR pathway can be modulated in macrophage cells by the presence of cryptococcal cells

Cryptococcus neoformans and Cryptococcus gattii are the etiological agents of cryptococcosis, a high mortality disease. The development of such disease depends on the interaction of fungal cells with macrophages, in which they can reside and replicate. In order to dissect the molecular mechanisms by...

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Detalles Bibliográficos
Autores principales: Piffer, Alícia C., dos Santos, Francine M., Thomé, Marcos P., Diehl, Camila, Garcia, Ane Wichine Acosta, Kinskovski, Uriel Perin, Schneider, Rafael de Oliveira, Gerber, Alexandra, Feltes, Bruno César, Schrank, Augusto, Vasconcelos, Ana Tereza R., Lenz, Guido, Kmetzsch, Lívia, Vainstein, Marilene H., Staats, Charley C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Genética 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8341293/
https://www.ncbi.nlm.nih.gov/pubmed/34352067
http://dx.doi.org/10.1590/1678-4685-GMB-2020-0390