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A STING-based fluorescent polarization assay for monitoring activities of cyclic dinucleotide metabolizing enzymes
Cyclic dinucleoties, such as cGAMP, c-di-GMP and c-di-AMP, are fascinating second messengers with diverse roles in both prokaryotes and eukaryotes. Consequently there is a need for simple and inexpensive methods for profiling these compounds in biological media, monitoring their synthesis or degrada...
Autores principales: | Karanja, Caroline W., Yeboah, Kofi S., Ong, Wilson W. S., Sintim, Herman O. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
RSC
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8341399/ https://www.ncbi.nlm.nih.gov/pubmed/34458783 http://dx.doi.org/10.1039/d0cb00187b |
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