Rational design of a stapled JAZ9 peptide inhibiting protein–protein interaction of a plant transcription factor

We herein describe the development of a stapled peptide inhibitor for a jasmonate-related transcription factor. The designed peptide selectively inhibited MYCs, master-regulators of jasmonate signaling, and selectively suppressed MYC-mediated gene expression in Arabidopsis thaliana. It is proposed a...

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Detalles Bibliográficos
Autores principales: Suzuki, Kaho, Takaoka, Yousuke, Ueda, Minoru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: RSC 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8341433/
https://www.ncbi.nlm.nih.gov/pubmed/34458795
http://dx.doi.org/10.1039/d0cb00204f

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8341433/
https://www.ncbi.nlm.nih.gov/pubmed/34458795
http://dx.doi.org/10.1039/d0cb00204f

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