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Phosphinate esters as novel warheads for activity-based probes targeting serine proteases
Activity-based protein profiling enables the specific detection of the active fraction of an enzyme and is of particular use for the profiling of proteases. The technique relies on a mechanism-based reaction between small molecule activity-based probes (ABPs) with the active enzyme. Here we report a...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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RSC
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8341442/ https://www.ncbi.nlm.nih.gov/pubmed/34458842 http://dx.doi.org/10.1039/d1cb00117e |