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Revision in the first steps of the biosynthesis of the red antibiotic prodigiosin: use of a synthetic thioester to validate a new intermediate
A biosynthetic pathway for the red-antibiotic, prodigiosin, was proposed over a decade ago but not all the suggested intermediates could be detected experimentally. Here we show that a thioester that was not originally included in the pathway is an intermediate. In addition, the enzyme PigE was orig...
Autores principales: | Couturier, Maxime, Bhalara, Hiral D., Monson, Rita E., Salmond, George P. C., Leeper, Finian J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
RSC
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8341465/ https://www.ncbi.nlm.nih.gov/pubmed/34458798 http://dx.doi.org/10.1039/d0cb00173b |
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