Early loss of T lymphocyte 4-1BB receptor expression is associated with higher short-term mortality in alcoholic hepatitis

OBJECTIVES: In alcoholic hepatitis (AH), dysfunctional T lymphocytes may contribute to the high mortality from infections. T lymphocyte activation is governed by the expression of co-stimulatory receptors such as 4-1BB balanced by inhibitory receptors such as Programmed Death receptor 1 (PD-1). 4-1B...

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Detalles Bibliográficos
Autores principales: Eriksen, Lotte Lindgreen, Nielsen, Morten Aagaard, Laursen, Tea Lund, Deleuran, Bent, Vilstrup, Hendrik, Støy, Sidsel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8341529/
https://www.ncbi.nlm.nih.gov/pubmed/34352016
http://dx.doi.org/10.1371/journal.pone.0255574

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8341529/
https://www.ncbi.nlm.nih.gov/pubmed/34352016
http://dx.doi.org/10.1371/journal.pone.0255574

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