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Early loss of T lymphocyte 4-1BB receptor expression is associated with higher short-term mortality in alcoholic hepatitis
OBJECTIVES: In alcoholic hepatitis (AH), dysfunctional T lymphocytes may contribute to the high mortality from infections. T lymphocyte activation is governed by the expression of co-stimulatory receptors such as 4-1BB balanced by inhibitory receptors such as Programmed Death receptor 1 (PD-1). 4-1B...
Autores principales: | Eriksen, Lotte Lindgreen, Nielsen, Morten Aagaard, Laursen, Tea Lund, Deleuran, Bent, Vilstrup, Hendrik, Støy, Sidsel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8341529/ https://www.ncbi.nlm.nih.gov/pubmed/34352016 http://dx.doi.org/10.1371/journal.pone.0255574 |
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