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Substrate inhibition by the blockage of product release and its control by tunnel engineering

Substrate inhibition is the most common deviation from Michaelis–Menten kinetics, occurring in approximately 25% of known enzymes. It is generally attributed to the formation of an unproductive enzyme–substrate complex after the simultaneous binding of two or more substrate molecules to the active s...

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Detalles Bibliográficos
Autores principales: Kokkonen, Piia, Beier, Andy, Mazurenko, Stanislav, Damborsky, Jiri, Bednar, David, Prokop, Zbynek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: RSC 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8341658/
https://www.ncbi.nlm.nih.gov/pubmed/34458806
http://dx.doi.org/10.1039/d0cb00171f