Short oligoalanine helical peptides for supramolecular nanopore assembly and protein cytosolic delivery

In this work we report a rational design strategy for the identification of new peptide prototypes for the non-disruptive supramolecular permeation of membranes and the transport of different macromolecular giant cargos. The approach targets a maximal enhancement of helicity in the presence of membr...

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Detalles Bibliográficos
Autores principales: Pazo, Marta, Salluce, Giulia, Lostalé-Seijo, Irene, Juanes, Marisa, Gonzalez, Francisco, Garcia-Fandiño, Rebeca, Montenegro, Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: RSC 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8341679/
https://www.ncbi.nlm.nih.gov/pubmed/34458796
http://dx.doi.org/10.1039/d0cb00103a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8341679/
https://www.ncbi.nlm.nih.gov/pubmed/34458796
http://dx.doi.org/10.1039/d0cb00103a

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