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Autoencoder based local T cell repertoire density can be used to classify samples and T cell receptors
Recent advances in T cell repertoire (TCR) sequencing allow for the characterization of repertoire properties, as well as the frequency and sharing of specific TCR. However, there is no efficient measure for the local density of a given TCR. TCRs are often described either through their Complementar...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8341707/ https://www.ncbi.nlm.nih.gov/pubmed/34310600 http://dx.doi.org/10.1371/journal.pcbi.1009225 |