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Antigen-Specific Treg Therapy in Type 1 Diabetes – Challenges and Opportunities

Regulatory T cells (Tregs) are key mediators of peripheral self-tolerance and alterations in their frequencies, stability, and function have been linked to autoimmunity. The antigen-specific induction of Tregs is a long-envisioned goal for the treatment of autoimmune diseases given reduced side effe...

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Detalles Bibliográficos
Autores principales: Serr, Isabelle, Drost, Felix, Schubert, Benjamin, Daniel, Carolin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8341764/
https://www.ncbi.nlm.nih.gov/pubmed/34367177
http://dx.doi.org/10.3389/fimmu.2021.712870