Cargando…

Deciphering the substrate recognition mechanisms of the heparan sulfate 3-O-sulfotransferase-3

The sulfation at the 3-OH position of a glucosamine saccharide is a rare modification, but is critically important for the biological activities of heparan sulfate polysaccharides. Heparan sulfate 3-O-sulfotransferase (3-OST), the enzyme responsible for completing this modification, is present in se...

Descripción completa

Detalles Bibliográficos
Autores principales: Wander, Rylee, Kaminski, Andrea M., Xu, Yongmei, Pagadala, Vijayakanth, Krahn, Juno M., Pham, Truong Quang, Liu, Jian, Pedersen, Lars C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: RSC 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8341778/
https://www.ncbi.nlm.nih.gov/pubmed/34458837
http://dx.doi.org/10.1039/d1cb00079a