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Optogenetic modulation of real-time nanoscale dynamics of HCN channels using photoactivated adenylyl cyclases
Adenosine 3′,5′-cyclic monophosphate (cAMP) is a key second messenger that activates several signal transduction pathways in eukaryotic cells. Alteration of basal levels of cAMP is known to activate protein kinases, regulate phosphodiesterases and modulate the activity of ion channels such as Hyper...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
RSC
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8341789/ https://www.ncbi.nlm.nih.gov/pubmed/34458814 http://dx.doi.org/10.1039/d0cb00124d |