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A Recurrent Cryptic MED14-HOXA9 Rearrangement in an Adult Patient With Mixed-Phenotype Acute Leukemia, T/myeloid, NOS

To define the fusion genes in T/myeloid mixed-phenotype acute leukemia (T/M MPAL), we performed transcriptome sequencing of diagnostic bone marrow samples from 20 adult patients. Our analysis identified a second instance of a recurrent MED14-HOXA9 chimeric gene resulting from the in-frame fusion of...

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Detalles Bibliográficos
Autores principales: Wang, Qian, Zhang, Ling, Zhu, Ming-qing, Zeng, Zhao, Fang, Bao-zhi, Xie, Jun-dan, Pan, Jin-lan, Wu, Chun-xiao, Wu, Ni, Zhang, Ri, Chen, Su-ning, Dai, Hai-ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8341862/
https://www.ncbi.nlm.nih.gov/pubmed/34367969
http://dx.doi.org/10.3389/fonc.2021.690218