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Protein degradation profile reveals dynamic nature of 20S proteasome small molecule stimulation

Small molecules have been discovered to stimulate the 20S core particle (CP) of the proteasome to degrade proteins. However, the impact a 20S CP stimulator can have on the regulation of protein levels has not been fully characterized. Previous studies have focused on using one kind of stimulator to...

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Detalles Bibliográficos
Autores principales: Coleman, Rachel A., Mohallem, Rodrigo, Aryal, Uma K., Trader, Darci J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: RSC 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8341874/
https://www.ncbi.nlm.nih.gov/pubmed/34458805
http://dx.doi.org/10.1039/d0cb00191k