The chemical biology of IL-12 production via the non-canonical NFkB pathway

Interleukin-12 (IL-12) has emerged as an attractive cytokine for cancer therapy because it has direct anti-cancer effects and additionally plays a critical role in enhancing checkpoint inhibitors. Given these multiple modes of actions, identifying means to pharmacologically induce IL-12 production i...

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Detalles Bibliográficos
Autores principales: Koch, Peter D., Pittet, Mikael J., Weissleder, Ralph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: RSC 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8341911/
https://www.ncbi.nlm.nih.gov/pubmed/34458756
http://dx.doi.org/10.1039/d0cb00022a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8341911/
https://www.ncbi.nlm.nih.gov/pubmed/34458756
http://dx.doi.org/10.1039/d0cb00022a

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