Elongation rate and average length of amyloid fibrils in solution using isotope-labelled small-angle neutron scattering

We demonstrate a solution method that allows both elongation rate and average fibril length of assembling amyloid fibrils to be estimated. The approach involves acquisition of real-time neutron scattering data during the initial stages of seeded growth, using contrast matched buffer to make the seed...

Descripción completa

Detalles Bibliográficos
Autores principales: Eves, Ben J., Doutch, James J., Terry, Ann E., Yin, Han, Moulin, Martine, Haertlein, Michael, Forsyth, V. Trevor, Flagmeier, Patrick, Knowles, Tuomas P. J., Dias, David M., Lotze, Gudrun, Seddon, Annela M., Squires, Adam M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: RSC 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8341957/
https://www.ncbi.nlm.nih.gov/pubmed/34458836
http://dx.doi.org/10.1039/d1cb00001b

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8341957/
https://www.ncbi.nlm.nih.gov/pubmed/34458836
http://dx.doi.org/10.1039/d1cb00001b

Ejemplares similares