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The role of P2Y12 in the kinetics of microglial self-renewal and maturation in the adult visual cortex in vivo

Microglia are the brain’s resident immune cells with a tremendous capacity to autonomously self-renew. Because microglial self-renewal has largely been studied using static tools, its mechanisms and kinetics are not well understood. Using chronic in vivo two-photon imaging in awake mice, we confirm...

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Detalles Bibliográficos
Autores principales: Mendes, Monique S, Le, Linh, Atlas, Jason, Brehm, Zachary, Ladron-de-Guevara, Antonio, Matei, Evelyn, Lamantia, Cassandra, McCall, Matthew N, Majewska, Ania K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8341987/
https://www.ncbi.nlm.nih.gov/pubmed/34250902
http://dx.doi.org/10.7554/eLife.61173